avatarDr Mehmet Yildiz

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Type II Diabetes and Fatty Liver Disease in a Juicy Bottle

Neighborly advice on the adverse effects of high-sugar-containing fruit juices on metabolic health

The author created the image with Adobe Firefly.

Over a year ago, our diabetic neighbors, both husband and wife in their mid-sixties, invited us to dinner. Knowing I don’t drink alcohol, they kindly offered me fruit juices. When I declined, mentioning I also avoid fruit juices, they seemed surprised and questioned why I’d avoid such healthy beverages. Before I could explain further, my intuitive and polite wife sitting beside me pinched my leg under the table so hard that I halted mid-sentence and informed them I had an allergy to fruit juice.

On another occasion, when I invited our neighbors for a walk along the beach, they expressed curiosity about how someone could be allergic to sugar. With my wife not present this time, I had the opportunity to explain the situation in a friendly manner. They found the explanation eye-opening and decided to discontinue drinking sugared and cheap fruit juices purchased from the grocery store.

Raising awareness about the adverse effects of sugared fruit juices on metabolic health is essential. Making informed dietary choices and encouraging healthier beverage options are pivotal in combating the rise of Type II Diabetes and its associated health complications. We should stop promoting sugary fruit juices as healthy.

I told them sugared fruit juices contain high fructose, and glucose levels can rapidly increase blood sugar levels upon consumption. The body’s response involves insulin secretion to regulate these elevated sugar levels. As they did not know insulin resistance, I explained it in simple language, as presented in the next section.

They understood that over time, consistent intake of high-sugar beverages can lead to insulin resistance, a key factor in Type II Diabetes.

Additionally, excessive fructose consumption contributes to fat accumulation in the liver, a condition known as non-alcoholic fatty liver disease (NAFLD), further exacerbating metabolic health issues.

Regular consumption of sugared fruit juices has been linked to an increased risk of developing Type II Diabetes. The spike in blood sugar levels from these beverages can strain the body’s insulin response, leading to insulin resistance.

Prolonged insulin resistance can eventually progress to Type II Diabetes, a chronic condition with profound health implications, including cardiovascular complications, kidney problems, nerve damage, and vision problems, as happened to my mother and several other relatives, as my family is carb-intolerant like me.

I also told them I had prediabetes in my younger years, and they were amazed when I reversed it with healthy lifestyle choices.

I told them the prevalence of sugared fruit juices in modern diets poses a significant public health concern. Widespread consumption of these beverages, especially among children and adolescents, contributes to rising rates of obesity and Type II Diabetes, as pointed out by medical doctor and educator Robert Lufkin, who inspired me for the title of my story in a recent tweet.

Many more caring medical doctors discussed the long-term consequences of high sugar-containing fruit juices on individual health and healthcare systems, straining resources to manage diabetes-related complications.

I also wrote a case study of a nutritionist friend titled Juliana’s Health Was Ruined When She Consumed Three Health Foods Excessively.

There is no conspiracy in this because anyone who understands nutritional biochemistry will know that fruit juices without fiber can significantly increase blood glucose and quickly turn into fat molecules, leading to obesity in adults and children.

Insights from the Body of Knowledge

Regrettably, there are instances where some scientists produce papers lacking rigorous standards, publishing them in non-peer-reviewed sources, leading to potential misinformation among the public. As scientists, we must maintain ethical standards, prioritizing disseminating accurate information rooted in the comprehensive body of accumulated knowledge.

An accumulated body of knowledge suggests that excessive sugar consumption, especially in liquid form, can disrupt metabolic health by affecting insulin sensitivity and promoting weight gain. Studies also highlight the impact of high-fructose corn syrup found in many sweetened beverages on metabolic function, contributing to metabolic syndrome and diabetes development.

For example, this systematic review and meta-analysis included four studies (191,686 participants, including 12,375 with type 2 diabetes) that investigated the association between sugar-sweetened fruit juice and the risk of incident type 2 diabetes and four studies (137,663 participants and 4,906 cases) investigated the association between 100% fruit juice and risk of incident type 2 diabetes.

A higher intake of sugar-sweetened fruit juice was significantly associated with risk of type 2 diabetes (RR = 1.28, 95%CI = 1.04–1.59, p = 0.02), while intake of 100% fruit juice was not associated with risk of developing type 2 diabetes (RR = 1.03, 95% CI = 0.91–1.18, p = 0.62).

Another systematic review and meta-analysis in BMJ concluded,

"Habitual consumption of sugar-sweetened beverages was associated with a greater incidence of type 2 diabetes, independently of adiposity.”

How Can We Enjoy Beverages and Fruit?

The author created the image with Adobe Firefly.

Encouraging reduced intake of sugared fruit juices, promoting healthier alternatives like water, mineral water, unsweetened tea, or coffee, and eating whole fruit might be helpful to lower the risk of insulin resistance and metabolic disorders like type II diabetes affecting 442 million and fatty liver disease impacting two billion people.

Twenty-five years ago, scientists were skeptical whether nonalcoholic fatty liver disease (NAFLD) was a clinical condition. However, after two decades, it became a global epidemic affecting around two billion people.

World Gastroenterology Organisation informs that NAFLD also has reached epidemic proportions among populations typically considered at low risk, with a prevalence of 15% in China and 14% in Japan.

Public health initiatives in many countries focus on education about the risks of high-sugar beverages and advocating for lower sugar content in processed foods, which can help address this issue.

I told my neighbors, who also smoke cigarettes, that over 50 countries have recently implemented taxes on sugar-sweetened beverages (SSBs) like tobacco products. In some of these countries, the effects of these taxes on consumption and reformulation of SSBs have been extensively studied.

My neighbors wondered why whole fruit is better than fruit juice. I told them that whole fruits offer distinct advantages over fruit juices due to their intact fiber content and slower sugar release.

When consuming whole fruits, the fiber present in the fruit slows down the digestion process, regulating the release of natural sugars into the bloodstream. This slower sugar release helps prevent rapid spikes in blood sugar levels, offering a more stable energy supply and avoiding the strain on insulin production.

Additionally, the fiber content in whole fruits aids digestion promotes satiety, and supports gut health. Conversely, fruit juices lack the fiber found in whole fruits, resulting in a quicker sugar release that can lead to abrupt spikes in blood sugar levels and potential negative impacts on metabolic health over time.

Thus, whole fruits present a more balanced nutritional option, offering essential vitamins, minerals, and fiber that support overall health and better sugar regulation.

The overconsumption of sugared fruit juices significantly impacts metabolic health, increasing the risk of developing Type II Diabetes and other metabolic conditions.

Therefore, reducing the intake of these high-sugar beverages and advocating for healthier alternatives are pivotal in preventing diabetes, fatty liver disease, and obesity and promoting overall well-being.

Here is how my neighbors gained better insights into insulin resistance.

Photo by Charlotte May from Pexels

I encouraged my neighbors to consult a specialized metabolic health practitioner focusing on Type II diabetes and NAFLD. As expected, their doctor identified significant insulin resistance in their bodies.

The first recommendation from the physician was straightforward: cease consuming fruit juices immediately and consume only one serving of whole fruits daily.

They understood that when high-sugar fruit juices are consumed, they swiftly increase blood sugar levels. In response, the pancreas releases insulin to help cells absorb and utilize the sugar.

Over time, regular consumption of these beverages can lead to insulin resistance, where cells become less responsive to insulin signals.

This resistance prompts the pancreas to produce more insulin (hyperinsulinemia), eventually leading to a state where the body can’t effectively maintain normal blood sugar levels and become diabetic.

Fortunately, when my neighbors ceased consuming fruit juices and reduced their intake of other refined carbohydrates, they witnessed a significant improvement in their diabetes within a year.

They are now on the path to reversing its effects through additional lifestyle changes, taking cues from the success story of my friends Mark and Lucy. This includes incorporating more exercise and practicing improved stress management.

I firmly believe that diabetes is preventable and reversible, as I have seen many diabetic patients achieve this goal in my circles. You can learn about my findings and perspectives in the attached story.

Conclusions and Takeaways

Excessive fructose consumption, often in high quantities in sugared fruit juices, increases visceral fat accumulation. The liver metabolizes fructose and converts it into fat, contributing to non-alcoholic fatty liver disease (NAFLD).

This condition, affecting over two billion people globally, involves the buildup of fat in the liver cells and can progress to more severe forms of liver disease, such as non-alcoholic steatohepatitis (NASH) and cirrhosis.

Prolonged consumption of high-sugar fruit juices and the resultant insulin resistance can ultimately lead to Type II Diabetes. The continuous strain on the body’s insulin production and response eventually leads to inadequate blood sugar control, resulting in elevated blood sugar levels characteristic of diabetes.

Beyond diabetes and NAFLD, high sugar intake from fruit juices can contribute to various metabolic disorders. It can lead to increased visceral fat deposition, a type of fat stored around internal organs, raising the risk of cardiovascular diseases, hypertension, and metabolic syndrome. Additionally, it can disrupt the balance of hormones like leptin resistance in appetite regulation, potentially leading to obesity.

Understanding these mechanisms highlights the significant impact of high-sugar fruit juices on metabolic health. Regular consumption of these beverages contributes to insulin resistance, NAFLD, Type II Diabetes, and an increased risk of various metabolic disorders, emphasizing the importance of reducing sugar intake for overall well-being.

The intricacies of sugar mirror a paradox akin to cholesterol, offering a complex interplay within our metabolism. Understanding this enigmatic element is pivotal in discerning both its benefits and drawbacks.

Sugar’s paradox emerges from its dual nature, serving as a vital component for cellular function. Glucose, primarily from carbs, is an indispensable energy source for every cell, ensuring our survival. Yet, intriguingly, excessive sugar triggers a toxic response in the body, creating a fascinating dichotomy.

To resolve this contradiction, our bodies possess gluconeogenesis, which enables glucose production even without sugar-rich foods. This mechanism allows me to flourish on a near zero-carb diet with one meal daily, accommodating my body’s carb intolerance while ensuring my survival and vitality.

The key takeaway of this story is to invite you to consider transitioning from fruit juices to whole fruits if they align with your preferences. Whole fruits offer a range of benefits, including fiber content that regulates sugar release, aiding in better blood sugar management.

Embracing whole fruits can be a flavorful and nutritious alternative to fruit juices, providing essential nutrients while supporting your metabolic health. Exploring and incorporating various fruits into your diet could lead to a more balanced and satisfying approach to enjoying natural sugars and maintaining overall well-being.

Thank you for reading my perspectives. I wish you a healthy and happy life.

I dedicate this story to Dr. Robert Lufkin, journalist Gary Taubes, and other professionals who remarkably educate people on the harmful effects of excessive sugar leading to the obesity epidemic.

Relevant Collection of Stories

To inform my new readers, I wrote numerous articles that might inform and inspire you. My topics include brain and cognitive function, significant health conditions, valuable nutrients, ketogenic lifestyle, self-healing, weight management, writing/reading, and humor. 100+ Insightful Life Lessons from My Circles for the Last 50+ Years

I publish my health and wellness stories on EUPHORIA. My posts do not include professional or health advice. I only document my reviews, observations, experiences, and perspectives to provide information and create awareness. Be Your Own Therapist in 10 Steps.

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Health
Diabetes
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