avatarNancy R. Gough, PhD

Summary

The web content describes an individual's experience with the Shingrix shingles vaccine, detailing the side effects and immune response following the first dose.

Abstract

The author of the web content recounts their personal journey after receiving the first dose of the Shingles vaccine, Shingrix, which had been difficult to obtain for nearly a year. The pharmacist had forewarned about potential side effects such as flu-like symptoms, chills, and pain at the injection site, which the author indeed experienced. Within hours of vaccination, the author felt body aches and had trouble sleeping due to discomfort and frequent bathroom visits. Despite initial reluctance to take pain medication for fear of affecting the immune response, the author eventually resorted to ibuprofen to manage the symptoms. The following day, the author experienced continued discomfort, fever, and remarkable redness and heat at the injection site, which are indicators of an active immune response facilitated by the vaccine's T-cell stimulating additive. The author reflects on a previous instance where they contracted shingles after not being recommended the vaccine at age 50, emphasizing the importance of vaccination for prevention. Despite the unpleasant side effects, the author is willing to endure them for the second dose to avoid the prolonged pain associated with shingles.

Opinions

  • The author acknowledges the temporary discomfort caused by
Image compiled by Nancy R. Gough, BioSerendipity, LLC from Varicellar zoster virus (Credit: NIAID from https://www.flickr.com/photos/niaid/5614251360),Shingles rash (Credit: K. L. Herman, CDC https://phil.cdc.gov/Details.aspx?pid=21505); Injection site redness (Credit: CDC and Medscape)

What to Expect from the Shingles Vaccine

The temporary discomfort is worth the long-term protection

I finally got my first dose of the shingles vaccine Shingrix. I had been trying to get the vaccine for close to a year, and it had been unavailable. The pharmacist warned me that I might feel like I had the flu, get chills, and find that my arm at the site of the injection was painful. She wasn’t kidding!

I got the vaccine around 4 PM. Within a few hours of receiving the vaccine, I started to ache. My arm where I had been injected hurt, but what really bothered me was the body aches, especially in my back. Around 10 PM, I went to bed and tried to sleep. I was up every hour or so to use the bathroom, and I just couldn’t get comfortable enough to fall asleep. By 2 AM, I gave up trying to sleep and took some ibuprofen. I didn’t want to interfere with my body’s immune response to the vaccine, but the discomfort was too much. I finally was able to sleep for a few hours. When I woke, I still felt awful and was running a fever. After taking a shower, I felt exhausted and had to lie down for a few hours, not really sleeping but not really fully awake either.

After getting up for the second time the day after getting the shot, I took some more ibuprofen. By the evening, the aches and fever had subsided. But my arm was amazingly hot to the touch and had a patch of red far larger than where the site of the injection was. Even the second day after the shot, the redness and heat in my arm is not any better.

These are all signs that the vaccine is working. My body is mounting an immune response. This version of the shingles vaccine causes such an extreme reaction because it contains a special additive that stimulates T cells. It is the T-cell response that declines as we get older.

At my check-up the year I turned 50, my doctor referred me for a colonoscopy. What he didn’t do was recommend that I get the shingles vaccine. I wound up getting shingles. I had to wait until the shingles had resolved before I could get the vaccine. Full coverage requires a second dose in 2 to 6 months.

Even though it hurts and I know I will lose a weekend to deal with the response to the vaccine, at least my chances of getting shingles again will be far lower. I’ll gladly take a weekend of discomfort to get the second shot instead of the months of pain that I endured when I had shingles.

Find out more about shingles and the two vaccines:

Prevent the Pain, Get the Shingles Vaccine

Health
Shingles
Vaccines
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